该分化系统可将人iPSC或ESC高效分化为多谱系前脑类器官
产生的前脑类器官呈现出典型的VZ、SVZ和CP样等结构,含有谷氨酰胺能、多巴胺能和GABA能等神经元,以及星形胶质、少突胶质及小胶质细胞
有试剂均化学成分明确、不含血清
该系统稳定性较好,目前已经通过过4种iPSC的测试
组分 | ||
• iForebrain Neuroectoderm Differentiation Kit | • iForebrain Neural Progenitor Differentiation Kit | • iForebrain Brain Growth and Maintenance Kit |
NE Media l (15mL) | NPC Media I (100mL) | MO Media I (200mL) |
NE Media ll (60mL) | NPC Media II (75mL) | MO Media Il (200mL) |
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